Skin tissue is highly responsive to hormonal signaling, particularly changes in estrogen levels during perimenopause and menopause. While collagen loss and visible skin aging are often associated with getting older, research continues to show that estrogen plays an important role in maintaining dermal integrity, hydration, elasticity, and overall tissue health.1 For healthcare providers, skin-related concerns may […]
Changing hormone levels can influence many aspects of physical and emotional health. For many women and men, hormone fluctuations may affect sleep quality, mood, mental clarity, body composition, energy levels, and overall quality of life. As more people learn about the effects of hormone imbalance, interest in hormone optimization and bioidentical hormone therapy has continued to grow. […]
Chronic stress can influence eating behaviors in ways that extend far beyond simple food cravings. Research continues to highlight the connection between stress, appetite regulation, sleep disruption, and changes in metabolic health.1 For many individuals, emotionally driven eating patterns are tied to a broader cycle involving cortisol imbalance, disrupted hunger signaling, fatigue, and reward-related eating behaviors. […]
Interest in peptides has grown significantly in recent years, particularly in conversations surrounding metabolism, recovery, and hormone health. While peptides are often discussed in connection with fitness and healthy aging, they serve a much broader purpose within the body. Peptides are naturally occurring chains of amino acids that play an important role in cellular communication and biological […]
Testosterone plays a central role in a man’s energy, strength, mood, and overall health. As awareness grows around the impact of hormone health on the body, more men are exploring bio-identical hormone replacement therapy (BHRT) with their local healthcare providers. Pellecome is a nationwide BHRT and supplement provider founded by Dr. Enrique G. Jacome, a board-certified OB-GYN […]
Healthcare providers nationwide are recognizing that metabolic health starts in the gut. At Pellecome, founded by board-certified OB-GYN Dr. Enrique G. Jacome in Gladstone, New Jersey, we have spent decades refining pellet-based BHRT systems while also understanding that long-term outcomes depend on more than hormone levels alone. With more than 30,000 pellet insertions performed since 1995, Dr. Jacome has […]
Changes in your skin, such as dryness, dullness, or unexpected breakouts, can be signs of deeper hormonal shifts. Estrogen impacts how your skin looks and feels, and the way your body metabolizes that estrogen can affect everything from moisture levels to inflammation. Pellecome’s DIM/I3C supplement is one way to support healthy hormone processing from within, which may […]
Midlife is a point when many patients begin reporting emotional changes that seem out of proportion to their life circumstances. Irritability, low mood, reduced stress tolerance, and emotional fatigue are common concerns raised in clinical settings, and they often prompt questions about adrenal health and declining hormone production. DHEA, a key adrenal hormone and precursor to […]
When daylight shrinks and temperatures drop, energy often follows. Many people find it harder to stay active during the winter, and that seasonal shift can impact everything from metabolism to appetite. The PellecomeFIT® BHRT Program, developed by hormone therapy expert Dr. Enrique G. Jacome, was designed to help counter challenges like these. Dr. Jacome built a safe […]
After weeks of big meals, sweet treats, and holiday cocktails, it’s no surprise that many patients tell their providers they feel bloated, sluggish, or a little out of sync hormonally. DIM and I3C supplements can potentially make a difference by helping the body process excess hormones and other by-products that tend to build up during periods […]
