Hot summer weather can make anyone feel drained, sweaty, or uncomfortable. But if you feel unusually sensitive to heat, wake up with night sweats, or notice sudden waves of warmth that seem to come out of nowhere, there may be more going on than the temperature outside. Shifting hormone levels can change how the body […]
When male patients present with fatigue, reduced libido, poor recovery, changes in body composition, or low motivation, testosterone is often part of the clinical conversation. While age-related hormonal decline is an important consideration, lifestyle factors can also shape how patients feel and how clinicians interpret symptoms and lab findings. Regular alcohol use is one lifestyle […]
When patients present with fatigue, poor stress tolerance, or cognitive complaints, clinicians often investigate endocrine contributors such as cortisol dysregulation, thyroid dysfunction, or metabolic abnormalities. However, hydration status may be an overlooked factor influencing many of these symptoms. Fluid balance is regulated through several endocrine pathways, including cortisol, aldosterone, and the renin-angiotensin-aldosterone system (RAAS). Even […]
If you regularly find yourself feeling sluggish a few hours after lunch, you’re not alone. Afternoon energy crashes are a common complaint, often bringing symptoms such as fatigue, brain fog, irritability, or difficulty concentrating. While a busy schedule or lack of sleep can certainly contribute, recurring afternoon fatigue may also be influenced by blood sugar […]
Skin tissue is highly responsive to hormonal signaling, particularly changes in estrogen levels during perimenopause and menopause. While collagen loss and visible skin aging are often associated with getting older, research continues to show that estrogen plays an important role in maintaining dermal integrity, hydration, elasticity, and overall tissue health.1 For healthcare providers, skin-related concerns may […]
Changing hormone levels can influence many aspects of physical and emotional health. For many women and men, hormone fluctuations may affect sleep quality, mood, mental clarity, body composition, energy levels, and overall quality of life. As more people learn about the effects of hormone imbalance, interest in hormone optimization and bioidentical hormone therapy has continued to grow. […]
Chronic stress can influence eating behaviors in ways that extend far beyond simple food cravings. Research continues to highlight the connection between stress, appetite regulation, sleep disruption, and changes in metabolic health.1 For many individuals, emotionally driven eating patterns are tied to a broader cycle involving cortisol imbalance, disrupted hunger signaling, fatigue, and reward-related eating behaviors. […]
Interest in peptides has grown significantly in recent years, particularly in conversations surrounding metabolism, recovery, and hormone health. While peptides are often discussed in connection with fitness and healthy aging, they serve a much broader purpose within the body. Peptides are naturally occurring chains of amino acids that play an important role in cellular communication and biological […]
Testosterone plays a central role in a man’s energy, strength, mood, and overall health. As awareness grows around the impact of hormone health on the body, more men are exploring bio-identical hormone replacement therapy (BHRT) with their local healthcare providers. Pellecome is a nationwide BHRT and supplement provider founded by Dr. Enrique G. Jacome, a board-certified OB-GYN […]
Healthcare providers nationwide are recognizing that metabolic health starts in the gut. At Pellecome, founded by board-certified OB-GYN Dr. Enrique G. Jacome in Gladstone, New Jersey, we have spent decades refining pellet-based BHRT systems while also understanding that long-term outcomes depend on more than hormone levels alone. With more than 30,000 pellet insertions performed since 1995, Dr. Jacome has […]