Stuck in a Weight Loss Plateau? Your Hormones Could Be the Reason

Have you been staring at the same number on the scale for weeks, even though you’ve been eating right and exercising? A plateau like this is not always about diet or willpower. In many cases, hormones are the hidden factor. When they fall out of balance, it can be much harder to see any progress.

The PellecomeFIT program was created to address this challenge. It combines bio-identical hormone replacement therapy (BHRT), peptides, and nutritional support to help get your hormones back into shape.

Behind the program is Pellecome, founded by Dr. Enrique G. Jacome, a board-certified Ob-Gyn. He has focused his career on developing innovative ways to restore hormonal balance through BHRT.

Signs Your Hormones May Be Stalling Your Weight Loss Progress

A stubborn plateau can be discouraging, especially when you feel like you are doing everything right. In many cases, the issue may be less about discipline and more about hormone imbalance. Here are some signs that hormones could be making your journey more difficult:

Frequent Sugar or Carb Cravings

Research has shown that stress hormones like cortisol, along with insulin resistance, are linked to weight gain and disrupted eating patterns. These changes can increase the drive for high-calorie foods and make cravings harder to resist.¹

Persistent Fatigue

Low thyroid hormones or imbalanced cortisol can drain your energy. Fatigue not only makes workouts harder but can also slow down your metabolism.²

Changes in Body Composition

Losing muscle tone or gaining fat around the midsection may point to shifts in testosterone, estrogen, or cortisol levels.^3,4 This pattern is especially common with age during menopause or andropause.

Mood Swings or Sleep Disruptions

Hormones that affect stress and metabolism also influence mood and sleep cycles.⁵ Poor rest or ongoing irritability can further complicate weight management.

Finding Balance Again With PellecomeFIT

Your hormones may indeed be the key to finally seeing the number on the scale go down. 

PellecomeFIT aims to support your health. Each part of the program plays a role: BHRT helps correct hormonal shifts, peptides may support metabolism and lean muscle, and nutrition guidance reinforces sustainable lifestyle habits.

You can find a Pellecome provider near you to discuss whether PellecomeFIT is a good match for your needs and learn more about how hormone balance may support lasting weight management.

1. Chao AM, Jastreboff AM, White MA, Grilo CM, Sinha R. Stress, cortisol, and other appetite-related hormones: Prospective prediction of 6-month changes in food cravings and weight. Obesity (Silver Spring) [Internet]. 2017;25(4):713–20. Available from: http://dx.doi.org/10.1002/oby.21790 
2. Ciobanu AM, Damian AC, Neagu C. Association between burnout and immunological and endocrine alterations. Rom J Morphol Embryol [Internet]. 2021;62(1):13–8. Available from: http://dx.doi.org/10.47162/RJME.62.1.02
3. Gharahdaghi N, Phillips BE, Szewczyk NJ, Smith K, Wilkinson DJ, Atherton PJ. Links between testosterone, oestrogen, and the growth hormone/insulin-like growth factor axis and resistance exercise muscle adaptations. Front Physiol [Internet]. 2020;11:621226. Available from: http://dx.doi.org/10.3389/fphys.2020.621226
4. Bavaresco A, Mazzeo P, Lazzara M, Barbot M. Adipose tissue in cortisol excess: What Cushing’s syndrome can teach us? Biochem Pharmacol [Internet]. 2024;223(116137):116137. Available from: http://dx.doi.org/10.1016/j.bcp.2024.116137
5. Morssinkhof MWL, van Wylick DW, Priester-Vink S, van der Werf YD, den Heijer M, van den Heuvel OA, et al. Associations between sex hormones, sleep problems and depression: A systematic review. Neurosci Biobehav Rev [Internet]. 2020;118:669–80. Available from: http://dx.doi.org/10.1016/j.neubiorev.2020.08.006