Can DIM Protect Against Breast Cancer?

woman checking her breast on blue background If you’re concerned about getting breast cancer, it’s important to explore natural preventive measures. One option that’s gaining attention is DIM (Diindolylmethane), a compound derived from cruciferous vegetables. 

Pellecome offers DIM supplements exclusively through our network of select providers as part of our commitment to supporting your health. But how does DIM work, and could it help reduce your risk?

DIM’s Role in Breast Cancer Prevention

DIM is a natural compound that your body makes when you eat cruciferous vegetables like broccoli and Brussels sprouts. It comes from another substance called Indole-3-Carbinol (I3C), which is also found in these veggies. Research suggests that DIM may help protect against breast cancer at different stages. 

DIM and Estrogen Metabolism

In women, estrogen helps control their reproductive system and affects things like body shape and breast development. When estrogen levels aren’t balanced, it can increase the risk of developing cancers, including breast cancer.2

DIM turns estrogen into forms that are less likely to cause harm while reducing the more dangerous forms.1 This balance can potentially lower the chances of estrogen-related breast cancers.

DIM’s Anti-Inflammatory Benefits

When your body experiences chronic inflammation, often caused by poor diet, stress, or persistent infections, it can increase your risk of getting cancer.3 

DIM has properties that help reduce ongoing inflammation. By calming down inflammatory responses, DIM helps create a healthier environment in your body, making it less likely for cancer to develop.

Supporting Detoxification

Your body can sometimes accumulate harmful toxins and hormones, like excess estrogen or chemicals from the environment and food. DIM supports your body’s natural detox process by making it easier for your liver to break down these substances.1 Clearing these toxins and hormones helps protect your body from things that could potentially lead to cancer.

Regulating Cell Growth

Cancer happens when cells grow out of control, ignoring the body’s normal signals to stop dividing. DIM influences the pathways that tell cells when to grow and when to stop. It can also encourage the body to get rid of damaged or potentially cancerous cells through a process called apoptosis, where the body naturally removes these harmful cells before they can build up and become a problem.1 

Take Control of Your Health With DIM

If breast cancer prevention is important to you, DIM supplements could be a valuable addition to your health routine. By supporting balanced estrogen levels, reducing inflammation, aiding detoxification, and regulating cell growth, DIM can potentially reduce your risk.

To get your DIM supplements or to learn more about how DIM can support your health, find a Pellecome provider in your area today. 

  1. Thomson CA, Ho E, Strom MB. Chemopreventive properties of 3,3′-diindolylmethane in breast cancer: evidence from experimental and human studies. Nutr Rev [Internet]. 2016 [cited 2024 Aug 21];74(7):432–43. Available from: http://dx.doi.org/10.1093/nutrit/nuw010 
  2. Al-Shami K, Awadi S, Khamees A, Alsheikh AM, Al-Sharif S, Ala’ Bereshy R, et al. Estrogens and the risk of breast cancer: A narrative review of literature. Heliyon [Internet]. 2023 [cited 2024 Aug 21];9(9):e20224. Available from: http://dx.doi.org/10.1016/j.heliyon.2023.e20224 
  3. Singh N, Baby D, Rajguru J, Patil P, Thakkannavar S, Pujari V. Inflammation and cancer. Ann Afr Med [Internet]. 2019 [cited 2024 Aug 21];18(3):121. Available from: http://dx.doi.org/10.4103/aam.aam_56_18 

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