Try Pellecome FIT® to Curb Vacation-Induced Cravings

Summer vacations tend to throw routines out the window. With more eating out and extra indulgences, cravings can start to ramp up. Pellecome FIT® can help keep you on track without missing out on the fun.

Pellecome FIT® is a medically guided program available through select providers across the United States. This program supports weight management through hormone balancing, peptide therapy, and customized supplements. Developed by Dr. Enrique Jacome, a board-certified OB-GYN and leader in hormone therapy since 1995, the program is designed for people who want to reduce cravings and support their metabolism.

Why Traveling Disrupts Your Healthy Eating Habits

Aside from being away from your usual routine, there’s also a science to how vacation habits can impact your hormones and hunger:

• Cortisol: Disrupted sleep and a packed or unpredictable schedule can cause your body to release more cortisol, the primary stress hormone. Elevated cortisol has been linked to increased appetite, especially for high-fat or high-sugar foods, and it can also encourage fat storage around the midsection.¹
• Ghrelin: Often called the “hunger hormone,” ghrelin rises when you don’t get enough sleep.² That spike can make you feel hungrier than you actually are, even if your energy needs haven’t increased.
• Leptin:  This hormone helps you recognize when you’re full. However, poor sleep or erratic eating can lower leptin levels, which may reduce satiety signals and lead to overeating.²

Hormonal shifts like these often go unnoticed until you realize your cravings are constant and your energy levels have dipped.

How Pellecome FIT® Helps Break the Cycle

Pellecome FIT® was developed to support weight management through a medical approach. This program includes the following:

BHRT

Bio-identical hormone replacement therapy (BHRT) helps stabilize hormone levels to keep your metabolism steady and your appetite in check. When hormones like estrogen, testosterone, thyroid, and cortisol are balanced, people may experience fewer cravings and more control over how their bodies respond to stress and food.³

Naltrexone

Naltrexone is used in the Pellecome FIT® program to help curb the urge to overeat by interfering with the brain’s reward pathways. It works as an opioid receptor antagonist, which means it can reduce the drive to eat in response to cues like stress, boredom, or the presence of highly palatable foods, not just true physiological hunger.⁴

Peptides

Peptides in the Pellecome FIT® program are used to support muscle growth, recovery, and metabolic function, which can help the body maintain stability during travel. Peptides act as signaling molecules that influence processes like fat metabolism and appetite regulation.⁵

Supporting Your Goals on the Go

Whether your metabolism tends to slow down or spike with stress, Pellecome FIT® offers tools to help your body stay balanced while you enjoy your trip. The program supports progress, not perfection, and helps reduce the guilt that can come with vacation eating habits.

Find a Pellecome provider near you to see if this program is the right fit for your health goals.

1. Hirotsu C, Tufik S, Andersen ML. Interactions between sleep, stress, and metabolism: From physiological to pathological conditions. Sleep Sci [Internet]. 2015;8(3):143–52. Available from: http://dx.doi.org/10.1016/j.slsci.2015.09.002 
2. van Egmond LT, Meth EMS, Engström J, Ilemosoglou M, Keller JA, Vogel H, et al. Effects of acute sleep loss on leptin, ghrelin, and adiponectin in adults with healthy weight and obesity: A laboratory study. Obesity (Silver Spring) [Internet]. 2023;31(3):635–41. Available from: http://dx.doi.org/10.1002/oby.23616 
3.  Hirschberg AL. Sex hormones, appetite and eating behaviour in women. Maturitas [Internet]. 2012;71(3):248–56. Available from: http://dx.doi.org/10.1016/j.maturitas.2011.12.016 
4. Mason AE, Laraia B, Daubenmier J, Hecht FM, Lustig RH, Puterman E, et al. Putting the brakes on the “drive to eat”: Pilot effects of naltrexone and reward-based eating on food cravings among obese women. Eat Behav [Internet]. 2015;19:53–6. Available from: http://dx.doi.org/10.1016/j.eatbeh.2015.06.008 
5. Rubinić I, Kurtov M, Likić R. Novel Pharmaceuticals in Appetite Regulation: Exploring emerging gut peptides and their pharmacological prospects. Pharmacol Res Perspect [Internet]. 2024;12(4):e1243. Available from: http://dx.doi.org/10.1002/prp2.1243