For practices incorporating hormone optimization into patient care, choosing a delivery method is only one part of building a thoughtful BHRT protocol. Appropriate evaluation, individualized dosing, insertion technique, monitoring, and follow-up all influence how pellet therapy fits into a broader treatment plan.
Pellecome® was founded by Enrique G. Jacome, MD, FACOG, a board-certified OB-GYN with extensive experience in women’s health, minimally invasive surgery, and hormone pellet insertion therapy. Our approach combines Bio-Identical Hormone Replacement Therapy (BHRT), pellet delivery technology, provider education, and clinical resources for healthcare professionals who want to incorporate hormone care into their practices.
What Is Pellet BHRT?
Pellet BHRT uses small hormone pellets that are placed beneath the skin by a trained healthcare professional. Once inserted, the pellets release the prescribed hormone gradually over time rather than requiring daily application or administration.
Hormone therapy should always be individualized. For menopausal women, The Menopause Society’s hormone therapy position statement emphasizes that treatment decisions depend on factors such as age, symptoms, health history, hormone type, dose, route of administration, and timing of therapy.
For men, the Endocrine Society’s testosterone therapy guideline recommends diagnosing testosterone deficiency only when compatible symptoms occur alongside consistently low testosterone levels confirmed with appropriate testing.
Where Pellet Therapy Fits Into Hormone Care
Patients may seek hormone evaluation for concerns such as hot flashes, night sweats, sexual health changes, sleep disruption, or symptoms associated with confirmed testosterone deficiency. Because many of these concerns overlap with other medical conditions, evaluation should look beyond symptoms alone.
For women, hormone therapy can be considered for concerns such as vasomotor and genitourinary symptoms of menopause when clinically appropriate. In men, testosterone treatment should follow a confirmed diagnosis rather than symptoms or a single laboratory result alone.
Pellecome’s women’s hormone health and men’s hormone health resources give practices additional educational material for conversations with patients.
Evaluating Candidates for Pellet BHRT
Before recommending pellet therapy, clinicians should consider the patient’s symptoms, medical history, medications, laboratory findings, risk factors, and treatment goals.
The appropriate workup will vary by patient. Hormone testing may be useful alongside other clinical information, but laboratory values should not be interpreted in isolation. Treatment also requires periodic review as symptoms, health status, and hormone needs change over time.
Rather than treating pellet therapy as a standardized protocol for every patient, the goal is to determine whether the delivery method fits the individual clinical picture.
Pellet Placement and Follow-Up
Hormone pellets are inserted subcutaneously during an office-based procedure. Pellecome’s Re3® Advanced Pellet Delivery System brings the primary insertion components into a single-use kit and facilitates linear retrograde pellet placement.
Insertion is only one part of treatment. Clinicians remain responsible for patient selection, hormone prescribing, dosing, sterile technique, aftercare, and ongoing monitoring. Follow-up may include symptom review and repeat laboratory testing
Benefits and Limitations of Pellet Delivery
For appropriate patients, pellet therapy provides a delivery option that does not require daily pills, creams, or patches. Hormone is released gradually between treatment visits, which may appeal to patients who prefer a longer-term delivery method.
Pellets also require an insertion procedure and cannot be adjusted in the same way as a daily medication once they have been placed. Hormone-related risks vary according to the hormone prescribed, dose, patient history, age, and other clinical fac
Why Choose Pellecome for Pellet BHRT?
Pellecome brings hormone pellets, insertion technology, clinician education, and practice resources together within one BHRT platform.
Dr. Jacome’s background in minimally invasive surgery and hormone pellet insertion helped inform Pellecome’s approach to delivery and training. Healthcare professionals can also access provider resources, pellet insertion training, and licensing resources as they build or expand hormone services.
This gives practices a framework that extends beyond the pellet itself, with education and clinical tools available as the service becomes part of ongoing patient care.
Frequently Asked Questions
Can Pellet BHRT Be Used for Both Women and Men?
Pellet hormone therapy may be considered for appropriately evaluated women and men when hormone treatment is clinically indicated.
How Often Are Hormone Pellets Placed?
Treatment intervals vary according to the hormone, dose, patient response, metabolism, and treatment plan. Follow-up helps determine when additional therapy should be considered.
Are Hormone Pellets Better Than Creams, Patches, or Injections?
No delivery method is universally best. The appropriate route depends on the patient’s diagnosis, preferences, medical history, and treatment goals.
What Happens if a Patient’s Hormone Needs Change?
Symptoms, lab findings, medical conditions, and treatment goals may change over time. Periodic reassessment allows clinicians to determine whether future dosing or the overall treatment plan should be modified.
Does Pellecome Train Providers in Pellet Insertion?
Yes. Pellecome’s provider training includes online education followed by physician-guided instruction in hormone pellet insertion.
How Can a Practice Begin Working With Pellecome?
Healthcare professionals can review Pellecome’s provider and licensing resources or contact us to discuss current partnership requirements.
Add Pellet BHRT to Your Clinical Services
Healthcare professionals considering pellet-based BHRT can work with Pellecome® to access hormone products, the Re3 delivery system, provider education, and practice resources. Contact us in Gladstone, NJ at 888-773-9969 to learn more about incorporating Pellecome into your hormone optimization services.
